Dose-dependent effects of mandibular protrusion on genioglossus activity in sleep apnoea.

نویسندگان

  • F R Almeida
  • S Tsuiki
  • Y Hattori
  • Y Takei
  • Y Inoue
  • A A Lowe
چکیده

mortality in chronic obstructive pulmonary disease. Thorax 2005; 60: 992–997. 3 Weatherall M, Clay J, James K, et al. Dose-response relationship of inhaled corticosteroids and cataracts: a systematic review and meta-analysis. Respirology 2009; 14: 983–990. 4 Weatherall M, James K, Clay J, et al. Dose-response relationship for risk of non-vertebral fracture with inhaled corticosteroids. Clin Exp Allergy 2008; 38: 1451–1458. 5 Hurst JR, Donaldson GC, Quint JK, et al. Temporal clustering of exacerbations in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2009; 179: 369–374. 6 Pietropaoli AP, Perillo IB, Perkins PT, et al. Smokers have reduced nitric oxide production by conducting airways but normal levels in the alveoli. Inhal Toxicol 2007; 19: 533–541. 7 Tsoukias NM, George SC. A two-compartment model of pulmonary nitric oxide exchange dynamics. J Appl Physiol 1998; 85: 653–666. 8 Sin DD, Lacy P, York E, et al. Effects of fluticasone on systemic markers of inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2004; 170: 760–765. 9 Masoli M, Weatherall M, Holt S, et al. Inhaled fluticasone propionate and adrenal effects in adult asthma: systematic review and meta-analysis. Eur Respir J 2006; 28: 960–967. 10 Sin DD, Man SF, Marciniuk DD, et al. The effects of fluticasone with or without salmeterol on systemic biomarkers of inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2008; 177: 1207–1214.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effect of genioglossus contraction on pharyngeal lumen and airflow in sleep apnoea patients.

The purpose of the present study was to quantify the mechanical effect of genioglossus stimulation on flow mechanics and pharyngeal cross-sectional area in patients with obstructive sleep apnoea, and to identify variables that determine the magnitude of the respiratory effect of tongue protrusion. The pressure/flow and pressure/cross-sectional area relationships of the velo- and oropharynx were...

متن کامل

Detection of right ventricular dysfunction by tissue Doppler imaging in asymptomatic patients with pulmonary sarcoidosis.

snoring and obstructive sleep apnea: a review. Sleep 2006; 29: 244–262. 3 Tsuiki S, Kobayashi M, Namba K, et al. Optimal positive airway pressure predicts oral appliance treatment response to sleep apnoea. Eur Respir J 2010; 35: 1098–1105. 4 Isono S. Upper airway muscle function during sleep. In: Loughlin GM, Varroll JL, Marcus CI, eds. Sleep and Breathing in Children. New York, Marcel Dekker, ...

متن کامل

Effects of a mandibular advancement device on genioglossus in obstructive sleep apnoea hypopnea syndrome.

OBJECTIVE To investigate effects of mandibular advancement device (MAD) therapy for obstructive sleep apnoea hypopnea syndrome (OSAHS) on the genioglossus contractile properties and fibre-type distribution. MATERIALS AND METHODS Thirty 6-month old male New Zealand white rabbits were randomised into three groups: OSAHS, MAD, and controls. Rabbits in Group OSAHS and Group MAD were established a...

متن کامل

Mandibular advancement and obstructive sleep apnoea: a method for determining effective mandibular protrusion.

The objectives of the study were to test the hypotheses that it is possible, during routine polysomnography (PSG), to prospectively identify favourable candidates for mandibular repositioning appliance (MRA) therapy in the treatment of obstructive sleep apnoea (OSA) and to accurately estimate an optimal protrusive distance at which to fabricate the MRA. A series of subjects underwent a remotely...

متن کامل

Tongue protrusion force and fatiguability in male and female subjects.

Limb and respiratory muscle (diaphragm) strength and fatiguability have been extensively studied in man and are known to vary with age and sex. However, in contrast to limb muscles and the diaphragm, force and fatiguability characteristics have not been studied in upper airway muscles. This study examines the hypotheses that tongue protrusion strength or fatiguability, determined by the propert...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The European respiratory journal

دوره 37 1  شماره 

صفحات  -

تاریخ انتشار 2011